Debanu Das, PhD
Co-Founder & CEO
Debanu has 15 years of experience in protein x-ray crystallography and structural biology. His expertise includes structure-function analysis of a broad range of proteins involved in cell development, cell wall recycling, DNA repair, human microbiome, cell signaling, viral replication and drug transport.
Prior to Accelero Biostructures, he served as Staff Scientist in the Structural Genomics Division at SSRL (Stanford Synchrotron Radiation Lightsource) at SLAC National Accelerator Laboratory, Menlo Park. There he determined crystal structures of several hundred novel proteins as part of the JCSG and established multiple productive partnerships with other renowned research groups for applying the results. He received his postdoctoral training at Lawrence Berkeley National Laboratory and University of California Berkeley on structural genomics and membrane protein crystallography with Sung-Hou Kim, a pioneer of structural genomics and founder of the drug discovery company Plexxikon.
As an industry expert, Debanu also consults with startups on structure-based drug discovery and business development. He holds an Integrated MS in Science and Engineering from the Indian Institute of Technology Kanpur and received his Ph.D. from Rutgers, NJ. He has also taken professional development courses in business and law in the Continuing Studies Program at Stanford University.
Ashley M. Deacon, PhD
Co-Founder & CSO
Ashley has 25 years of experience in synchrotron-based protein crystallography research. His professional experience and passion lies in the development and application of new technology to high impact structural biology research. Prior to founding Accelero Biostructures, Ashley held multiple positions at SSRL at SLAC National Accelerator Laboratory, Menlo Park, including Staff Scientist, Senior Staff Scientist, and Group Leader of the Structural Genomics Division and JCSG Structure Determination Core.
Ashley helped develop a synchrotron-integrated platform for high quality structure determination which JCSG applied to a broad array of important biological problems, including the de novo structure determination of hundreds of proteins from the human microbiome, human stem cell and T-cell biology and the prokaryotic cell cycle. This led to the determination of about 1500 novel 3D structures, including several protein-protein and protein-nucleotide complexes and numerous protein-ligand complexes.
During postdoctoral training at Cornell University, Ashley worked closely with Nobel Laureate Herbert Hauptman to apply “direct methods” of structure determination to a broad class of biological problems using synchrotron-based multi-wavelength anomalous dispersion and ultra-high resolution diffraction data. Ashley holds a Ph.D. from the University of Manchester, UK, and is an alumni of the Stanford Manager Academy at Stanford University.