About Us
Since its inception in 2015, Accelero Biostructures has been providing state-of-the-art, high- throughput protein X-ray crystallography-driven drug discovery and structural biology solutions to pharmaceutical/biotechnology companies using its ABS-Service℠ and ABS-OneStep℠ platforms.
Accelero capitalizes on more than 15 years of high-throughput protein X-ray crystal structure determination at the Joint Center for Structural Genomics (JCSG) consortium that was headed by Ian Wilson. The JCSG was comprised of The Scripps Research Institute, La Jolla; Genomics. Institute of the Novartis Research Foundation, La Jolla; Sanford Burnham Prebys Medical Discovery Institute, La Jolla; and SLAC National Accelerator Laboratory, Menlo Park.
The JCSG was funded through the National Institutes of Health-National Institute of General Medical Sciences’ Protein Structure Initiative and through considerable investments from participating institutions.
The JCSG developed a robust gene to structure pipeline with a multi-institutional, industry-like operation. The primary drivers were efficiency and cost.
More than 1500 novel protein structures were solved, resulting in over 300 publications.
“Accelero” signifies our mission to “accelerate” drug discovery, and it also relates to an “accelerator”, which is a crucial part of extremely brilliant X-ray light sources called synchrotrons. We use them for collecting X-ray diffraction data to solve protein crystal structures.
The graphic depicts a slanted view of a synchrotron. The central California Gold color portrays the brilliance of a synchrotron light source and also represents our home state California, with its rich pioneering history and reputation from the California gold rush to the birthplace of biotechnology and the hub of cutting-edge technological developments. This central hub binds the upper and lower colors of Cardinal Red and Founder’s Rock, which represent the colors of Stanford University/SLAC National Accelerator Laboratory and University of California Berkeley/Lawrence Berkeley National Laboratory, respectively, the training grounds of our founders and represent two of the core institutions that have helped to build the leading biosciences hub in the world in San Francisco.